Top 4 Dog Immune System Support Supplements

Top 4 Dog Immune System Support Supplements

Alex Seilis

Dogs, being close to the ground, are frequently exposed to various environmental toxins, chemicals, and pesticides that can impact their overall well-being. So a strong immune system is essential for dogs to maintain their health and vitality.

The food your dog consumes can also contribute to immune system stress. Commercial pet foods often contain ingredients like fluoride, aflatoxins, heterocyclic amines, and acrylamides which can accumulate in your dog's body over time.

The good news is there are natural ways to support your dog's immune system and help mitigate the impact of environmental and dietary toxins.

In this article, we'll explore some effective and natural options to support your dog’s immune system and keep them healthy and vibrant.

The 4 Best Dog Supplements For Immune Support

1. Echinacea

Echinacea, also known as the purple coneflower, has been valued for its health-promoting properties since it was discovered by Plains Indians and later popularized in the late 1800s. This herb is renowned for its ability to support immune function in both humans and animals.

Echinacea works by activating macrophages, which are immune cells that target and eliminate foreign invaders. It may also support the production of T-cells and chemokines, which aid in directing immune cells to infection sites.

Echinacea's benefits stem from its active compounds, echinacoside and echinacein, which contribute to its health-supporting effects:

  • Supports immune health: Helps prepare the immune system to respond to potential threats.
  • Maintains overall health: Contains properties beneficial for maintaining overall health and well-being.
  • Supports respiratory health: Offers support for respiratory health conditions such as dog flu and kennel cough.
  • Supports cellular health: May help in maintaining the health of cells.

When To Give Your Dog Echinacea

Echinacea is most effective when given before exposure to potential health stressors:

  • Before meeting new dogs: To help prepare the immune system.
  • Ahead of stressful events: Such as traveling or visits to the vet.
  • Before and during boarding: To maintain health in kennels or daycare settings.

How To Give Your Dog Echinacea

The best form of echinacea for dogs is a low-alcohol glycerin extract, as it is absorbed quickly and more palatable due to glycerin's sweet taste. The general dosage recommendation is 1/2 ml per 15 lbs of body weight, administered up to three times daily.

While some herbalists recommend taking breaks from echinacea to maintain its effectiveness, others support continuous use. It's best to consult with a holistic veterinarian to determine the optimal dosing schedule for your dog.

2. Functional Mushrooms

Functional mushrooms have been used for centuries to support health and wellness, and they offer significant benefits for dogs as well. These mushrooms are packed with bioactive compounds that can help maintain a healthy immune system. When used in combination, they can be even more effective.


Reishi mushrooms, often referred to as the "mushroom of immortality," are highly regarded for their health-supporting properties. They contain polysaccharides that contribute to cellular health and help maintain normal immune function.

Reishi mushrooms also have compounds like triterpenes, which support the body's natural response to cellular damage.

Benefits of Reishi Mushrooms:

  • Supports immune health: Helps maintain a balanced immune response.
  • Promotes cellular health: Contains compounds that support the health of cells.
  • Overall wellness: Contributes to maintaining overall health and vitality.


Maitake mushrooms are renowned for their unique polysaccharide compound, beta-1,6-glucan, which supports the body's natural defense mechanisms. Research has shown that maitake mushrooms can help maintain cellular health and support overall wellness.

Benefits of Maitake Mushrooms:

  • Support immune function: Help maintain a healthy immune system.
  • Promote cellular health: Support the body's natural defenses.
  • Maintain wellness: Contribute to overall health.

Turkey Tail

Turkey tail mushrooms are rich in beta-glucans and polysaccharide-K (PSK), compounds that support the immune system. Turkey tail mushrooms have been studied for their ability to maintain cellular health and support the body's natural defenses.

Benefits Of Turkey Tail Mushrooms:

  • Support immune health: Helps support a healthy immune system.
  • Maintain cellular health: Contains compounds beneficial for cellular health.
  • Overall support: Contributes to maintaining overall wellness.

When to Give Your Dog Functional Mushrooms

  • Aging dogs: For maintaining health as your dog ages.
  • Dogs with health challenges: To support overall wellness during illness.
  • For daily health: As part of a regular health maintenance routine.

How to Give Your Dog Functional Mushrooms

It's best to use a blend of several functional mushrooms for optimal benefits. When choosing a supplement, ensure it is a double-extracted product made from whole mushrooms, not just mycelium, for maximum efficacy. Follow the dosing instructions on the product label, and consult your veterinarian for personalized advice.

Functional mushrooms offer a natural way to help maintain your dog's health and support their immune system, making them a valuable addition to your dog's wellness routine.

3. Colostrum and Lactoferrin

Colostrum, the nutrient-rich first milk produced by mammals immediately after giving birth, is a powerful supplement for dogs. It contains essential growth factors and antibodies that support immune health and overall development. Bovine colostrum, which comes from cows, is particularly beneficial because it is highly concentrated in these immune factors.

Benefits of Colostrum and Lactoferrin

  • Supports immune health: Contains immunoglobulins that help maintain a healthy immune system.
  • Promotes digestive health: Provides growth factors that support the integrity of the gut lining.
  • Overall wellness: Contains lactoferrin, which supports cellular health and normal immune function.

Colostrum is also rich in proline-rich polypeptide (PRP), an immunomodulator that helps maintain a balanced immune response. Additionally, it contains transfer factors, small molecules that transfer immunity information from one animal to another, enhancing immune readiness.

When To Give Your Dog Colostrum And Lactoferrin

  • Digestive support: If your dog experiences digestive discomfort or needs gut health support.
  • Immune health: To help maintain a healthy immune system.
  • Overall health maintenance: For general health support and wellness.

How To Give Your Dog Colostrum And Lactoferrin

Colostrum is most effective when given on an empty stomach but can also be mixed with a small amount of yogurt or broth. The recommended dose is 1/8 teaspoon per 25 lbs of body weight, given twice daily. Follow the dosing instructions on the product label and consult your veterinarian for specific recommendations.

4. Probiotics

Probiotics are beneficial bacteria that play a crucial role in maintaining gut health and supporting the immune system. About 90% of your dog’s immune system is located in the gut, making probiotics essential for overall health.

Benefits Of Probiotics

  • Supports gut health: Helps maintain a healthy balance of gut bacteria.
  • Maintains immune health: Contributes to a healthy immune response.
  • Promotes digestive health: Supports normal digestion and reduces occasional digestive upset.

Probiotics like bifidobacteria and Lactobacillus acidophilus help maintain a healthy gut environment by competing with harmful bacteria and supporting the production of protective mucosal layers. They also produce short-chain fatty acids that support overall gut health.

When To Give Your Dog Probiotics

  • Digestive support: If your dog has occasional digestive issues or soft stools.
  • Immune support: To help maintain a healthy immune system.
  • Overall wellness: As part of a regular health maintenance routine.

How To Give Your Dog Probiotics

Probiotics should be given at least a few times each week for preventive health and daily if your dog is experiencing health challenges. Look for high-quality probiotic supplements designed for dogs and follow the dosing instructions on the label. Consult your veterinarian for personalized advice.

How To Choose Immune Support Supplements For Your Dog

When selecting immune system supplements for your dog, it's important to choose high-quality, natural supplements that are specifically formulated for pets. Look for products that have undergone rigorous testing and are free from harmful additives.

Here are some tips to help you make the best choices:

  • Consult with your veterinarian: Always consult with your holistic veterinarian before starting any new supplement regimen for your dog. They can provide personalized recommendations based on your dog's health needs.
  • Research the ingredients: Choose supplements with natural, well-researched ingredients known for their health benefits. Avoid products with artificial additives, fillers, or preservatives.
  • Check for quality assurance: Look for supplements that are manufactured in facilities that follow good manufacturing practices (cGMP), the National Animal Supplement Council seal (NASC), and have third-party testing for quality and purity.

By choosing the right immune system supplements, you can help support your dog’s overall health and well-being.

The Importance Of A Healthy Diet For Immune Health

In addition to supplements, a healthy diet plays a crucial role in maintaining your dog's immune system. Feeding your dog a balanced, nutritious diet helps provide the essential nutrients needed to support their immune function.

Here are some pointers to keep in mind:

  • Whole foods: Opt for whole, unprocessed foods whenever possible. Fresh fruits, vegetables, and lean proteins are excellent choices.
  • Avoid toxins: Minimize exposure to toxins by choosing organic foods and avoiding foods with artificial additives and preservatives.
  • Hydration: Ensure your dog has access to clean, fresh water at all times to support overall health and hydration.

Exercise And Lifestyle Factors For Everyday Support

Regular exercise and a healthy lifestyle are also important for maintaining your dog’s immune system.

Physical activity helps keep your dog’s body strong and can reduce stress, which can negatively impact immune health.

There are three simple things you can do to give your dog a healthy lifestyle:

  1. Regular exercise: Ensure your dog gets regular exercise appropriate for their age, breed, and health condition. Activities like walking, running, and playing can help keep them fit and healthy.
  2. Stress management: Minimize stress by providing a stable, loving environment for your dog. Regular routines and positive reinforcement can help reduce anxiety.
  3. Mental stimulation: Provide mental stimulation through interactive toys, training, and enrichment activities to keep your dog’s mind sharp and engaged.

Final Thoughts

By incorporating natural immune system supplements like echinacea, functional mushrooms, colostrum, and probiotics, you can help support your pup's immune health.

Additionally, a balanced diet, regular exercise, and a healthy lifestyle play crucial roles in supporting your dog’s immune function.

That said, always consult with your veterinarian before introducing new supplements or making significant changes to your dog’s routine.


How can I support my dog's immune system? To support your dog's immune system, provide a balanced diet rich in antioxidants like vitamin C and vitamin E, amino acids, and quality products such as immune-boosting supplements that support pets with seasonal allergies and other concerns.

Do immune supplements work for dogs? Yes, immune supplements can work for dogs by providing extra support through proven formulas containing vitamins, antioxidants, and minerals to help protect your pup's immune health.

What is a homemade immune booster for dogs? A homemade immune support for dogs can include ingredients like vitamin-rich vegetables, lean meats, and antioxidant-rich treats, which are great products for supporting a strong immune system.

Do probiotics help dogs immune system? Yes, probiotics help dogs' immune systems by supporting gut health, which is essential for supporting immune protection.